Home Therapy Company
Spiro Medical

Exploring Neuromodulation for Severe Asthma

Spiro Medical is developing an implantable neuromodulation system designed to address the unmet needs of patients with severe, uncontrolled asthma.

Patient breathing freely

Advancing Care Through
Thoughtful Innovation

Our approach combines deep clinical insights with advanced neuromodulation technology.

Neuromodulation Approach

Targeted spinal nerve stimulation designed to modulate respiratory function and reduce asthma symptom burden in severe cases.

Precision
Targeting

Implantable device technology engineered for consistent, reliable therapeutic delivery at the thoracic spinal level.

Clinical
Development

Evidence-based approach supported by renowned experts and advancing through structured clinical trials.

Understanding Severe Asthma

Severe asthma represents a complex clinical challenge affecting approximately 5–10% of all asthma patients. Despite optimized pharmacological therapy, many patients continue to experience significant symptom burden, frequent exacerbations that can be life-threatening, and reduced quality of life.

Current treatment options, while valuable, may not adequately address the underlying neurological components of respiratory regulation. Neuromodulation offers a promising complementary therapeutic approach by targeting autonomic nervous system pathways that influence bronchial tone and inflammatory responses.

Spiro Medical's investigational therapy is designed to provide a novel intervention for patients who have exhausted conventional treatment options.

Lung illustration

Frequently Asked Questions

Neuromodulation therapy involves the use of electrical stimulation to modulate nerve activity and alter physiological function. In the context of respiratory disease, it targets autonomic pathways that regulate bronchial tone.
The therapy is designed for patients with severe, uncontrolled asthma who have not responded adequately to conventional pharmacological treatments including biologics and high-dose corticosteroids.
Spiro Medical is conducting clinical studies to evaluate the safety and efficacy of Pulmonary Neuromodulation in carefully selected patients.
Potential benefits include reduced frequency of asthma exacerbations, improved lung function, decreased reliance on medication and improved quality of life for patients with severe asthma.

Partner with Innovation

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